How to get to Antofagasta?
To get to Antofagasta from any point in the south you must take the Ruta 5 (the Pan-American Highway). It is 564 km from Copiapó and 898 km from La Serena. If you are coming from the north, you must take Ruta 5 towards the south. It is 205 km from Calama and 493 from Iquique.
There are daily services from all the nearest cities, as well as from Santiago. You can inquire at the bus terminal of any city.